基因名

IL23A

别名

SGRF;Interleukin-23 subunit alpha;IL-23 subunit alpha;IL-23-A;Interleukin-23 subunit p19;IL-23p19;UNQ2498;PRO5798

全名

interleukin 23，alpha subunit p19

英文名称

ActivAb^TMRecombinant human IL23A protein

中文名称

ActivAb^TM白细胞介素23亚基α

规格

10ug ; 50ug ; 100ug ; 1mg

外观(性状)

Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)

纯度

≥85% by SDS-PAGE.

储存条件

Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.

运输条件

The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.

浓度

1mg/ml by SDS-PAGE.

Swiss Prot

Q9NPF7

Gene ID

51561

交叉反应

Human Mouse Rat (Pig Horse)

分子量

19kDa

区间范围

1-170aa

背景说明

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

应用

Immunology research

来源

E.coli

纯化方法

NI-NTA affinity purification

溶剂

Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)

内毒素

Not measured

生物活性

NO

标签信息

With a 6×His tag at the N/C-terminus.